Background: After years of disuse of chloroquine (CQ) as first-line anti-malarial drug in Ghana, reports from molecular studies conducted in parts of the country indicate varying prevalence of 76 mutation in the pfcrtgene. ...

Background: Thymol, a natural monoterpene phenol is not only relevant clinically as an anti-microbial, antioxidant and anti-inflammatory agent but also holds the prospect as a natural template for pharmaceutical semi ...

Poor lipid and glucose regulation increases the risk for the development of major cardiovascular diseases and other organ damage. The study evaluated the serum glucose and lipid lowering effects of the 70% (v /v) ethanolic ...

Summary Unlike other countries, the chloroquine resistant marker Pfcrt T76 mutant has remained fairly stable in Ghana several years after official disuse of chloroquine. Certain mutations inPfmdr1may potentiate Pfcrt T76, ...

. Background: In sub-Saharan Africa where sickle cell trait (SCT) and malaria is prevalent, significant proportions of blood donors may be affected by one or more of these abnormalities.The haemato-biochemical ...

Mango in Ghana is targeted as the next non-traditional export crop that is expected to fetch the highest foreign exchange for the country than cocoa. However, production and export constraints caused by fruit fly Bactrocera ...

Brain serotonin (5-hydroxytryptamine, 5-HT) system dysfunction is implicated in exaggerated fear responses triggering various anxiety-, stress-, and trauma-related disorders. However, the underlying mechanisms are not well ...

The enormous burden placed on populations worldwide by mosquito-borne diseases, most notably malaria and dengue, is currently being tackled by the use of insecticides sprayed in residences or applied to bed nets, and in ...

The clinical outcome of falciparum malaria in endemic areas is influenced by erythrocyte polymorphisms including the ABO blood groups. Studies have reported association of ABO blood group to resistance, susceptibility, and ...

Herbal medicinal products play a significant role in the management of diabetes and other chronic diseases either as a monotherapy or in combination with allopathic treatments. The hypoglycemic activity of a Ghanaian herbal ...