Abstract:
Objective: This study was conducted to determine the prevalence and distribution of high-risk human papillomavirus
(HR-HPV) genotypes among sexually active women in Tenkodogo, Burkina Faso.
Methods: Among 131 sexually active women attending the Tenkodogo Urban Medical Center, endocervical
samples were collected prior to screening for precancerous lesions. After viral DNA extraction, fourteen HR-HPV
genotypes were characterized by real-time multiplex PCR in these cervical samples.
Results: The mean age was 35.5 ± 9.5 years. Of the 131 women, 45 were infected with at least one HR-HPV
genotype. The prevalence of HR-HPV infection among these women was 34.4%. Among the 45 oncogenic HPVinfected
women, single HR-HPV genotype was found in 55.6% while 44.4% were infected with more than one
HR-HPV genotype. The most frequent genotypes were HPV56 (36.5%), HPV66 (36.5%).
Conclusion: Tenkodogo women included in this study had a higher prevalence of HPV 56, HPV 66. A larger study
with a more representative sample would therefore be needed to determine predominant oncogenic genotypes in
the subregion and especially in cancer cases.
