APOBEC3G expression and HIV-1 infection in Burkina Faso

Compaore, Tegwinde Rebeca; Soubeiga, Serge Theophile; Abdoul Karim Ouattara

dc.contributor.author	Compaore, Tegwinde Rebeca
dc.contributor.author	Soubeiga, Serge Theophile
dc.contributor.author	Abdoul Karim Ouattara
dc.date.accessioned	2021-04-08T11:59:57Z
dc.date.available	2021-04-08T11:59:57Z
dc.date.issued	2018-06
dc.identifier.uri	http://hdl.handle.net/123456789/5305
dc.description.abstract	Abstract APOBEC3G is a potent inhibitor of HIV-1 replication, and act by deaminating cytidines in uracil on the negative strand of the viral cDNA. In this case-control study, APOBEC3G expression in subjects’ naïve to HAART infected by HIV-1 and the effect of APOBEC3G polymorphism on its expression were evaluated. The results show that the HIV-1 infected carriers of the G minor alleles of the variant rs8177832 had a higher expression of APOBEC3G mRNA than the controls carriers of the G minor allele. APOBEC3G polymorphisms could play an important role in the modulation of the HIV-1.	en_US
dc.language.iso	en	en_US
dc.subject	APOBEC3G	en_US
dc.subject	HIV-1	en_US
dc.title	APOBEC3G expression and HIV-1 infection in Burkina Faso	en_US
dc.type	Article	en_US