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Now showing items 1-20 of 454

Risk factors for meningococcal meningitis

Hodgson, A; Smith, T; Gagneux, S; Adjuik, M; Pluschke, G; Mensah, N K; Binka, F; Genton, B (PubMed, 2001-09)

Meningococcal meningitis is a major cause of morbidity and mortality in the meningitis belt of sub- Saharan Africa where it occurs in epidemics every 8- 12 years. Risk factors for the disease in this setting remain largely ...
The RNA-binding protein SUP-12 controls muscle- specific splicing of the ADF/cofilin pre-mRNA in C. elegans

Anyanful, Akwasi; Ono, Kanako; Johnsen, Robert C.; Ly, Hinh; Jensen, Victor; Baillie, David L.; Ono, Shoichiro (THE JOURNAL OF CELL BIOLOGY, 2004-11)

T issue-specific alternative pre-mRNA splicing is essen- tial for increasing diversity of functionally different gene products. In Caenorhabditis elegans, UNC- 60A and UNC-60B, nonmuscle and muscle isoforms of actin ...
Tissue expression of four troponin I genes and their molecular interactions with two troponin C isoforms in Caenorhabditis elegans

Ruksana, Razia; Kuroda, Kazuki; Terami, Hiromi; Bando, Tetsuya; Kitaoka, Shun; akaya, Tomohide T; Sakube, Yasuji; Kagawa, Hiroaki (Genes to Cells, 2005)

Gene duplication is a major genetic event that can produce multiple protein isoforms. Comparative sequence and functional analysis of related gene products can provide insights into protein family evolution. To characterize ...
Paralysis and killing of Caenorhabditis elegans by enteropathogenic Escherichia coli requires the bacterial tryptophanase gene

Dolan-Livengood, Jennifer M.; Lewis, Taiesha; Sheth, Seema; DeZalia, Mark N.; Sherman, Melanie A.; Kalman, Lisa V.; Benian, Guy M.; Kalman, Daniel (Molecular Microbiology, 2005)

Pathogenic Escherichia coli, including enteropatho- genic E. coli (EPEC), enterohaemorrhagic E. coli (EHEC), enteroinvasive E. coli (EIEC) and enterotoxi- genic E. coli (ETEC) are major causes of food and water-borne ...
Cluster randomised trial of Intermittent preventive treatment for malaria in infants in area of high, seasonal transmission in Ghana

Chandramohan, Daniel; Owusu-Agyei, Seth; Carneiro, Ilona; Awine, Timothy; Amponsa-Achiano, Kwame; Mensah, Nathan; Jaffar, Shabbar; Baiden, Rita; Hodgson, Abraham; Binka, Fred; Greenwood, Brian (BJM, 2005-10)

Objective To evaluate the effects of intermittent preventive treatment for malaria in infants (IPTi) with sulfadoxine-pyrimethamine in an area of intense, seasonal transmission. Design Cluster randomised placebo ...
Sachet Drinking Water In Accra: The Potential Threats Of Transmission Of Enteric Pathogenic Protozoan Organisms

Kwakye-Nuako, G.; Borketey, P.B; Mensah-Attipoe, I.; Asmah, R.H; Ayeh-Kumi, P.F (2007-06)

Background: The recent introduction of sachet water to consumers was to provide safe, hygienic and affordable instant drinking water to the public. Although this is a laudable idea current trends seem to suggest that ...
Severe falciparum malaria in young children of the Kassena-Nankana district of northern Ghana

Oduro, Abraham R; Koram, Kwadwo A; Rogers, William; Atuguba, Frank; Ansah, Patrick; Anyorigiya, Thomas; Ansah, Akosua; Anto, Francis; Mensah, Nathan; Hodgson, Abraham (Malaria Journal, 2007-07-27)

Study design: Severe falciparum malaria in children was studied as part of the characterization of the Kassena-Nankana District Ghana for future malaria vaccine trials. Children aged 6–59 months with diagnosis suggestive ...
Epidemiology And Herbal Treatment Options In Some Selected Areas Of Central Region Of GhanaEpidemiology And Herbal Treatment Options In Some Selected Areas Of Central Region Of Ghana

Ampomah, Paulina (University of Cape Coast, 2008-01)

Incidence of malaria in the Central Region of Ghana was investigated to determine age group and sex vulnerability as well as the parasite species distribution, haemoglobin status of patients and herbs used in treating ...
Predictive Performance of Renal Function Equations Among Ghanaians Presenting with Chronic Kidney Disease

Owiredu, William K.B.A.; Ephraim, Richard K. Dadzie; Amidu, Nafiu; Eghan, Benjamin A; Quaye, Lawrence (Journal of Medical Sciences, 2008-05)

This study specifically evaluate the predictive performance and accuracy of the six renal function equations in patients presenting with CKD in our community. The results of these predictive equations for 50 patients using ...
A Randomized, Controlled Trial of Intermittent Preventive Treatment with Sulfadoxine- Pyrimethamine, Amodiaquine, or the Combination in Pregnant Women in Ghana

Clerk, Christine Alexandra; Bruce, Jane; Affipunguh, Pius Kaba; Mensah, Nathan; Hodgson, Abraham; Greenwood, Brian; Chandramohan, Daniel (The Journal of Infectious Diseases, 2008-10-15)

Background. The use of sulfadoxine-pyrimethamine (SP) for intermittent preventive treatment in pregnancy (IPTp) is threatened by the spread of resistance to SP. Therefore, we studied the efficacy, safety, and tolerance ...
A Comparison Of The Antimicrobial (Antifungal) Properties Of Garlic, Ginger And Lime On Aspergillus Flavus, Aspergillus Niger And Cladosporium Herbarum Using Organic And Water Base Extraction Methods

Tagoe, D; Baidoo, S; Dadzie, I (The Internet Journal of Tropical Medicine, 2009)

The study aim at comparing the antimicrobial (antifungal) properties of garlic, ginger and lime on Aspergillus flavus, Aspergillus niger and Cladosporium herbarum using organic and water base extraction. Pure cultures ...
A study of Bacterial Contamination of Ghanaian Currency Notes in Circulation

Tagoe, D; Baidoo, S; Dadzie, I; Ahator, D (The Internet Journal of Microbiology, 2009)

The study aimed at determining the presence, type and nature of bacterial contamination of Ghanaian currency notes in circulation. One hundred currency notes of different denominations were randomly collected from sellers ...
Characterization of focal liver lesions with SonoVue®- enhanced sonography: International multicenter-study in comparison to CT and MRI

Trillaud, Hervé; Bruel, Jean-Michel; Valette, Pierre-Jean; Vilgrain, Valérie; Schmutz, Gérard; Oyen, Raymond; Jakubowski, Wieslaw; Danes, Jan; Valek, Vlastimil (World Journal of Gastroenterology, 2009)

IM: To evaluate in a multicenter study whether the sonographic characterization of focal liver lesions can be improved using SonoVue®-enhancement; and to compare this method with computed tomography (CT) and magnetic ...
Pre-referral rectal artesunate to prevent death and disability in severe malaria: a placebo-controlled trial

Gomes, M F; Faiz, M A; Gyapong, J O; Warsame, M; Agbenyega, T; Babiker, A; Baiden, F; Yunus, E B; Binka, F; Clerk, C; Folb, P; Hassan, R; Hossain, M A; Kimbute, O; Kitua, A; Krishna, S; Makasi, C; Mensah, N; Mrango, Z; Olliaro, P; Peto, R; Peto, T J; Rahman, M R; Ribeiro, I; Samad, R; White, N J (Lancet, 2009-02-14)

Background Most malaria deaths occur in rural areas. Rapid progression from illness to death can be interrupted by prompt, eﬀective medication. Antimalarial treatment cannot rescue terminally ill patients but could be ...
Levels Of Serum Alanine/Aspartate Aminotransferase And Urea In Apparently Healthy Rural Community In Ghana: A Case Study In Sabin-Akrofrom And Trede In The Ashanti Region

Boampong, J.N.; Acquah, S.; Mate-Siakwa, P.; Mensah, D. Osei-Bonsu; Nyarko, A. (Journal of Ghana Science Association, 2009-06)

Serum alanine aminotransferase (ALT), aspartate aminotransferase (AST) and urea levels were assessed in 27 males (mean age 32.33 yrs) and in 34 females (mean age 27.85yrs) Ghanaian ru- ral dwellers to determine the ...
Levels of serum alanine/aspartate aminotransferase and urea in apparently healthy rural community in Ghana. A case study in Subin-Akrofrom and Trede in the Ashanti Region.

Boampong, Johnson Nyarko; Acquah, S.; Mate-Siakwa, P.; Mensah, D. Osei Bonsu; Nyarko, A. (University of Cape Coast, 2009-06)

Serum alanine aminotransferase (ALT), aspartate aminotransferase (AST) and urea levels were assessed in 27 males (mean age 32.33 yrs) and in 34 females (mean age 27.85yrs) Ghanaian ru- ral dwellers to determine the ...
CSN-5, a Component of the COP9 Signalosome Complex, Regulates the Levels of UNC-96 and UNC-98, Two Components of M-lines in Caenorhabditis elegans Muscle

Miller, Rachel K.; Qadota, Hiroshi; Stark, Thomas J.; Mercer, Kristina B.; Wortham, Tesheka S.; Anyanful, Akwasi; Benian, Guy M. (Molecular Biology of the Cell, 2009-08-01)

In Caenorhabditis elegans two M-line proteins, UNC-98 and UNC-96, are involved in myofibril assembly and/or mainte- nance, especially myosin thick filaments. We found that CSN-5, a component of the COP9 signalosome complex, ...
Sero-prevalence of toxoplasmosis among patients visiting the Korle-Bu Teaching Hospital, Accra, Ghana

Ayeh-Kumi, P.F; Opoku, A.G; Kwakye-Nuako, G.; Dayie, N.T.K.D; Asmah, R.H; Obeng Nkrumah, N.; Lartey, M.; Sagoe, A.; Attipoe, M.i; Osafo, K.A; Kretchy, J.P (2010)

oxoplasmosis is a disease caused by the intracellular protozoan parasite Toxoplasma gondii. It affects up to about one third of the human population worldwide. Toxoplasmosis in neonates and immunocompromised patients can ...
Prevalence and antibiogram of Klebsiella species recovered from clinical samples at the Komfo Anokye teaching hospital in Ghana

Feglo, P.K; Acheampong, D. O; Gbedema, S.Y (Bioinfo Publications, 2010)

Background and Objective: The antibiogram of the various species of Klebsiella implicated in many infections in Ghana are not known. This study was designed to determine the antibiogram of the various species of Klebsiella ...
REDICTIVE EQUATIONS, OXIDATIVE AND METABOLIC RISK FACTORS AMONG GHANAIAN PATIENTS PRESENTING WITH CHRONIC KIDNEY DISEASE

EPHRAIM, RICHARD KOBINA DADZIE (KWAME NKRUMAH UNIVERSITY OF SCIENCE & TECHNOLOGY, 2010-02)

Current recommendations emphasize the need to assess kidney function using creatinine- based predictive equations to optimize the care of patients presenting with chronic kidney disease. The most widely used equations ...

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