Browsing by Author "Abuaku, Benjamin"

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Plasmodium falciparum genetic factors rather than host factors are likely to drive resistance to ACT in Ghana

Hodoameda, Peter; Duah‑Quashie, Nancy Odurowah; Hagan, Charles Oheneba; Matrevi, Sena; Abuaku, Benjamin; Koram, Kwadwo; Quashie, Neils Ben (BMC, 2020)

Background: Artemisinin-based combination therapy (ACT) partner drugs, currently used in Ghana are lumefantrine, amodiaquine and piperaquine. Plasmodium falciparum isolates with reduced susceptibility to these partner ...
Prevalence of Plasmodium falciparum delayed clearance associated polymorphisms in adaptor protein complex 2 mu subunit (pfap2mu) and ubiquitin specific protease 1 (pfubp1) genes in Ghanaian isolates

Adams, Tryphena; Ennuson, Nana Aba A.; Quashie, Neils B.; Futagbi, Godfred; Matrevi, Sena; Hagan, Oheneba C. K.; Abuaku, Benjamin; Koram, Kwadwo A.; Duah, Nancy O. (Biomed Central, 2018)

Background: Plasmodium falciparum delayed clearance with the use of artemisinin-based combination therapy (ACTs) has been reported in some African countries. Single nucleotide polymorphisms (SNPs) in two genes, P. falciparum ...

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