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Browsing by Author "Compaore, Tegwinde Rebeca"

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APOBEC3G expression and HIV-1 infection in Burkina Faso

Compaore, Tegwinde Rebeca; Soubeiga, Serge Theophile; Abdoul Karim Ouattara (2018-06)

Abstract APOBEC3G is a potent inhibitor of HIV-1 replication, and act by deaminating cytidines in uracil on the negative strand of the viral cDNA. In this case-control study, APOBEC3G expression in subjects’ naïve to ...
APOBEC3G is a potent inhibitor of HIV-1 replication, and act by deaminating cytidines in uracil on the negative strand of the viral cDNA. In this case-control study, APOBEC3G expression in subjects’ naïve to HAART infected by HIV-1 and the effect of APOBEC3G polymorphism on its expression were evaluated. The results show that the HIV-1 infected carriers of the G minor alleles of the variant rs8177832 had a higher expression of APOBEC3G mRNA than the controls carriers of the G minor allele. APOBEC3G polymorphisms could play an important role in the modulation of the HIV-1 dissemination

Compaore, Tegwinde Rebeca; Soubeiga, Serge Theophile; Ouattara, Abdoul Karim; Obiri-Yeboah, Dorcas; Tchelougou, Damehan; Maiga, Mamoudou; Assih, Maleki; Bisseye, Cyrille; Bakouan, Didier; Compaore, Issaka Pierre; Dembele, Augustine; Martinson, Jeremy; Simpore, Jacques (PLOS ONE, 2016)

Studies on host factors, particularly the APOBEC3G gene, have previously found an association with AIDS progression in some populations and against some HIV-1 strains but not others. Our study had two main objectives: ...
APOBEC3G Variants and Protection against HIV-1 Infection in Burkina Faso

Compaore, Tegwinde Rebeca; Soubeiga, Serge Theophile; Ouattara, Abdoul Karim; Obiri-Yeboah, Dorcas; Tchelougou, Damehan; Maiga, Mamoudou (2016-01)

Studies on host factors, particularly the APOBEC3G gene, have previously found an association with AIDS progression in some populations and against some HIV-1 strains but not others. Our study had two main objectives: ...
HBV/HIV co-infection and APOBEC3G polymorphisms in a population from Burkina Faso

Compaore, Tegwinde Rebeca; Diarra, Birama; Assih, Maleki; Obiri-Yeboah, Dorcas; Soubeiga, Serge Theophile; Ouattara, Abdoul Karim; Tchelougou, Damehan; Bisseye, Cyrille; Bakouan, Didier Romuald; Compaore, Issaka Pierre; Dembele, Augustine; Djigma, Wendkuuni Florencia; Simpore, Jacques (BMC Infectious Diseases, 2016)

Background: Apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3G (APOBEC3G) is a potent host defense factor, which interferes with HIV-1 and HBV. Our study had three objectives, to screen a population of HIV-1 ...
Major Polymorphisms of Genes Involved in Homocysteine Metabolism in Malaria Patients in Ouagadougou, Burkina Faso

Yameogo, Noé; Bazie, Bapio Valérie Elvira Jean Télesphore; Ouattara, Abdoul Karim; Yameogo, Pouiré; Compaore, Tegwinde Rebeca; Obiri-Yeboah, Dorcas; Djigma, Florencia Wenkuuni; Karou, Simplice Damintoti; Simpore, Jacques (Malaria Research and Treatment, 2017)

This study analyzed the four main polymorphisms of the genes in homocysteine metabolism in malaria patients. Forty-two randomly selected subjects, diagnosed positive for Plasmodium falciparum, were included. The four ...
World Hepatitis Day in Burkina Faso, 2016: Awareness, Screening, Identification of HBV Markers, HBV/HCV Coinfection, and Vaccination

Diarra, Birama; Ouattara, Abdoul Karim; Djigma, Florencia Wendkuuni; Compaore, Tegwinde Rebeca; Obiri-Yeboah, Dorcas; Traore, Lassina; Soubeiga, Serge Theophile; Bado, Prosper; Yara, Justine; Pietra, Virginio; Ouedraogo, Paul; Bougouma, Alain; Sanogo, Rokia; Simpore, Jacques (Hepatitis Monthly, 2017)

Background: Hepatitis B virus (HBV) can cause chronic hepatitis, cirrhosis, and hepatocellular carcinoma. Coinfection with hepatitis C virus (HCV)/HBV leads to a higher risk of liver damage. Development of HBV awareness ...

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