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Browsing by Author "Dadzie, Isaac"

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5′-UTR of malS increases the invasive capacity of Salmonella enterica serovar Typhi by influencing the expression of bax

Gong, Mingyu; Xu, Shungao; Jin, Yue; Zhang, Ying; Dadzie, Isaac; Zhang, Xiaolei; Wang, Zhexin; Zhu, Yunxia; Ni, Bin; Sheng, Xiumei; Huang, Xinxiang (Future Microbiol, 2015)

Aim: An RNA-seq analysis recently identified a 236-nucleotide transcript upstream from malS in Salmonella enterica serovar Typhi. Here, we investigated its molecular characteristics and function. Materials & methods: ...
Antimicrobial Profile and Asymptomatic Urinary Tract Infections among Pregnant Women Attending Antenatal Clinic in Bolgatanga Regional Hospital, Ghana

Fosu, Kwabena; Quansah, Elvis; Dadzie, Isaac (University of Cape Coast, 2019-07)

Urinary tract infection (UTI) in pregnancy is associated with significant morbidity for both the mother and the baby. Proper investigation and prompt treatment are needed to prevent the serious life-threatening condition ...
Antimicrobial Profile and Asymptomatic Urinary Tract Infections among Pregnant Women Attending Antenatal Clinic in Bolgatanga Regional Hospital, Ghana

Fosu, Kwabena; Quansah, Elvis; Dadzie, Isaac (Microbiology Research Journal International, 2019)

Background: Urinary tract infection (UTI) in pregnancy is associated with significant morbidity for both the mother and the baby. Proper investigation and prompt treatment are needed to prevent the serious life-threatening ...
Bispecific Antibodies (bsAbs): Promising Immunotherapeutic Agents for Cancer Therapy

Acheampong, Desmond O.; Adokoh, Christian K.; Ampomah, Paulina; Agyirifo, Daniel S.; Dadzie, Isaac; Ackah, Francis A.; Asiamah, Ernest A. (University of Cape Coast, 2017)

Abstract: Antibodies have become the preferred therapeutic treatment option for cancers. Antibody therapy is associated with low toxic profile and specific in its activity, unlike chemotherapy and ra- diotherapy. Types ...
Bispecific Antibodies (bsAbs): Promising Immunotherapeutic Agents for Cancer Therapy

Acheampong, Desmond O.; Adokoh, Christian K.; Ampomah, Paulina; Agyirifo, Daniel S.; Dadzie, Isaac; Ackah, Francis A.; Asiamah, Ernest A. (Protein & Peptide Letters, 2017)

Abstract: Antibodies have become the preferred therapeutic treatment option for cancers. Antibody therapy is associated with low toxic profile and specific in its activity, unlike chemotherapy and ra- diotherapy. Types ...
Cytotoxic and Antioxidant Effects of Antimalarial Herbal Mixtures

Dadzie, Isaac; Avorgbedo, Shaibu Adams; Appiah-Opong, Regina; Cudjoe, Obed (International Journal of Microbiology, 2020)

Many developing countries depend on herbal mixtures as the ﬁrst line and cost-eﬀective therapy for malaria. These mixtures with such curative tendencies may also be a source of toxicity to host cells. On the other hand, ...
Design of a Comprehensive Biochemistry and Molecular Biology Experiment: Phase Variation Caused by Recombinational Regulation of Bacterial Gene Expression

Sheng, Xiumei; Xu, Shungao; Lu, Renyun; Dadzie, Isaac; Xueyi, Zhang; Haifang, Zhang; Huifang, Wang; Zheng, Qiao; Xinxiang, Huang (Biochemistry and Molecular Biology Education, 2014-02-17)

Scientific experiments are indispensable parts of Biochem- istry and Molecular Biology. In this study, a comprehensive Biochemistry and Molecular Biology experiment about Sal- monella enterica serovar Typhi Flagellar ...
Diagnosis and Treatment Outcome of Smear Positive Pulmonary Tuberculosis: Retrospective study in Kpando Municipal, Ghana

Acheampong, Desmond O.; Opoku, Richard; Boye, Alex; Agyirifo, Daniel S.; Dadzie, Isaac; Barnie, Prince A.; Kwakye-Nuako, Godwin; Nyandzi, Francis (Journal of Advances in Medicine and Medical Research, 2018)

Background: Smear microscopy remains the primary tool for the detection of tuberculosis in Ghana. Laboratory diagnosis of active tuberculosis cases by sputum smear microscopy is a critical component of Directly Observed ...
Diagnosis and Treatment Outcome of Smear Positive Pulmonary Tuberculosis: Retrospective study in Kpando Municipal, Ghana

Acheampong, Desmond O.; Opoku, Richard; Boye, Alex; Agyirifo, Daniel S.; Dadzie, Isaac; Barnie, Prince A.; Francis Nyandzi; Kwakye-Nuako, Godwin (University of Cape Coast, 2018-03-15)

Background: Smear microscopy remains the primary tool for the detection of tuberculosis in Ghana. Laboratory diagnosis of active tuberculosis cases by sputum smear microscopy is a critical component of Directly Observed ...
Diagnostic Yield of Fluorescence and Ziehl-Neelsen Staining Techniques in the Diagnosis of Pulmonary Tuberculosis: A Comparative Study in a District Health Facility

Dzodanu, Eben Godsway; Afrifa, Justice; Acheampong, Desmond Omane; Dadzie, Isaac (University of Cape Coast, 2019-03)

Despite the recent advancement in diagnostic methods, the smear microscopy remains the gold standard for the diagnosis of pulmonary tuberculosis in high burden countries like Ghana. Notwithstanding, fluorescence staining ...
The Effectiveness of Dipstick for the Detection of Urinary Tract Infection

Dadzie, Isaac; Quansah, Elvis; Dakorah, Mavis Puopelle; Abiade, Victoria; Takyi-Amuah, Ebenezer; Adusei, Richmond (Canadian Journal of Infectious Diseases and Medical Microbiology, 2019)

Background. The balance between the choices of UTI diagnostic tools in most primary care settings has been settled for by the more rapid, less labour-intensive dipstick. This study aimed to evaluate the eﬀectiveness of ...
Fis Is Essential for the Stability of Linear Plasmid pBSSB1 and Affects the Motility of Salmonella enterica Serovar Typhi

Zhang, Haifang; Ni, Bin; Zhao, Xin; Dadzie, Isaac; Du, Hong; Wang, Qiang; Xu, Huaxi; Huang, Xinxiang (PLoS ONE, 2012-07)

pBSSB1 is a 27 kb non-bacteriophage-related linear plasmid first found in Salmonella enterica serovar Typhi (S. Typhi), but the mechanism underlying the replication of pBSSB1 is currently unknown. Previous reports showed ...
Geographical Distribution of β-Lactam Resistance among Klebsiella spp. from Selected Health Facilities in Ghana

Quansah, Elvis; Barnie, Prince Amoah; Acheampong, Desmond Omane; Obiri-Yeboah, Dorcas; Mills, Richael Odarkor; Asmah, Ebenezer; Cudjoe, Obed; Dadzie, Isaac (University of Cape Coast, 2019-09-03)

β-Lactam-resistant Klebsiella isolates continue to cause multidrug resistance infections worldwide. This study aimed to describe the geographical distribution of extended spectrum β-lactamase (ESBL), AmpC β-lactamase (AmpC), ...
Geographical Distribution of β-Lactam Resistance among Klebsiella spp. from Selected Health Facilities in Ghana

Quansah, Elvis; Barnie, Prince Amoah; Acheampong, Desmond Omane; Obiri-Yeboah, Dorcas; Mills, Richael Odarkor; Asmah, Ebenezer; Cudjoe, Obed; Dadzie, Isaac (Tropical Medicine and Infectious Disease, 2019)

β-Lactam-resistant Klebsiella isolates continue to cause multidrug resistance infections worldwide. This study aimed to describe the geographical distribution of extended spectrum β-lactamase (ESBL), AmpC β-lactamase (AmpC), ...
Geographical Distribution of β-Lactam Resistance among Klebsiella spp. from Selected Health Facilities in Ghana

Quansah, Elvis; Barnie, Prince Amoah; Acheampong, Desmond Omane; Obiri-Yeboah, Dorcas; Mills, Richael Odarkor; Asmah, Ebenezer; Cudjoe, Obed; Dadzie, Isaac (Tropical Medicine and Infectious Disease, 2019)

β-Lactam-resistant Klebsiella isolates continue to cause multidrug resistance infections worldwide. This study aimed to describe the geographical distribution of extended spectrum β-lactamase (ESBL), AmpC β-lactamase ...
Identification and Characterization of a Cis-Encoded Antisense RNA Associated with the Replication Process of Salmonella enterica Serovar Typhi

Dadzie, Isaac; Xu, Shungao; Ni, Bin; Zhang, Xiaolei; Zhang, Haifang; Sheng, Xiumei; Xu, Huaxi; Huang, Xinxiang (PLOS ONE, 2013-04)

Antisense RNAs that originate from the complementary strand of protein coding genes are involved in the regulation of gene expression in all domains of life. In bacteria, some of these antisense RNAs are transcriptional ...
Nucleic Acid Amplification Testing Detects HIV Transmission Risk in Serologically- Tested Blood Donor Units

Dadzie, Isaac; Muniru, Shemau; Adu, Patrick; Cudjoe, Obed (Journal of Clinical and Diagnostic Research, 2018)

ntroduction: Blood transfusion is an essential life-saving intervention in the healthcare delivery. Mandatory screening of donor units helps prevent transfusion-transmissible infections, such as Human Immunodeficiency ...
Persistent exposure to wood smoke is associated with variations in biochemical and hematological indices among regular wood burners in the Cape Coast metropolis, Ghana

Dadzie, Emmanuel K.; Ephraim, Richard K.D.; Afrifa, Justice; Quaicoe, Richard; Bediako, Benjamin S.; Duku, Benedict I.; Adjetey, Townshed; Dadzie, Isaac (Scientiﬁc African, 2019)

Background: Acute and chronic exposure to wood smoke is associated with adverse health effects. This study investigated the potential effect of persistent exposure to woodsmoke on hematological and biochemical indices ...
Profile and Antimicrobial Susceptibility Pattern of Bacterial Isolates from Infected Wounds of Patients Attending Berekum Holy Family Hospital in Ghana

Dadzie, Isaac; Quansah, Nicholas; Dadzie, Emmanuel Kingsley (University of Cape Coast, 2019-03)

Wound management and care after an infection has been known to present a major concern to healthcare professionals. Its association with increased trauma, discomfort and financial burden to patients bring to bear the ...
Profile and Antimicrobial Susceptibility Pattern of Bacterial Isolates from Infected Wounds of Patients Attending Berekum Holy Family Hospital in Ghana

Dadzie, Isaac; Quansah, Nicholas; Dadzie, Emmanuel Kingsley (Journal of Advances in Medicine and Medical Research, 2018)

Background: Wound management and care after an infection has been known to present a major concern to healthcare professionals. Its association with increased trauma, discomfort and financial burden to patients bring to ...

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