Browsing by Author "Duah, Nancy O."

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Prevalence of Plasmodium falciparum delayed clearance associated polymorphisms in adaptor protein complex 2 mu subunit (pfap2mu) and ubiquitin specific protease 1 (pfubp1) genes in Ghanaian isolates

Adams, Tryphena; Ennuson, Nana Aba A.; Quashie, Neils B.; Futagbi, Godfred; Matrevi, Sena; Hagan, Oheneba C. K.; Abuaku, Benjamin; Koram, Kwadwo A.; Duah, Nancy O. (Biomed Central, 2018)

Background: Plasmodium falciparum delayed clearance with the use of artemisinin-based combination therapy (ACTs) has been reported in some African countries. Single nucleotide polymorphisms (SNPs) in two genes, P. falciparum ...
Synergism between Pfcrt and Pfmdr1 genes could account for the slow recovery of chloroquine sensitive Plasmodium falciparum strains in Ghana after chloroquine withdrawal

Asare, Kwame K.; Boampong, Johnson N.; Duah, Nancy O.; Afoakwah, Richmond; Sehgal, Rakesh; Quashie, Neils B. (University of Cape Coast, 2015)

Summary Unlike other countries, the chloroquine resistant marker Pfcrt T76 mutant has remained fairly stable in Ghana several years after official disuse of chloroquine. Certain mutations inPfmdr1may potentiate Pfcrt T76, ...

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