Browsing by Author "Ekem, Ivy"

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  • Association between eNOS Gene Polymorphism (T786C and VNTR) and Sickle Cell Disease Patients in Ghana 
    Antwi-Boasiako, Charles; Dzudzor, Bartholomew; Kudzi, William; Doku, Alfred; Dale, Campbell Andrew; Sey, Fredericka; Otu, Kate Hgar; Boatemaa, Gifty Dankwah; Ekem, Ivy; Ahenkorah, John; Achel, Daniel Gyingiri; Aboagye, Elvis Twumasi; Donkor, Eric S. (Diseases, 2018)
    Endothelial nitric oxide synthase (eNOS) variants have been found to be associated with several vascular disorders as well as the pathogenesis of sickle cell disease (SCD) complications such as vaso-occlusive crises (VOC). ...
  • A case–control study of prevalence of anemia among patients with type 2 diabetes 
    Antwi-Bafour, Samuel; Hammond, Samuel; Kofi Adjei, Jonathan; Ekem, Ivy; Martin-Odoom, Alexander (2016-03)
    Background: Anemia is defined as a reduction in the hemoglobin concentration of blood, which consequently reduces the oxygen-carrying capacity of red blood cells such that they are unable to meet the body’s physiological needs. ...
  • A case–control study of prevalence of anemia among patients with type 2 diabetes 
    Antwi-Bafour, Samuel; Hammond, Samuel; AdjeI, Jonathan Kofi; Kyeremeh, Ransford; Martin-Odoom, Alexander; Ekem, Ivy (Journal of Medical Case Reports, 2016)
    Background: Anemia is defined as a reduction in the hemoglobin concentration of blood, which consequently reduces the oxygen-carrying capacity of red blood cells such that they are unable to meet the body’s physiological ...
  • Elevated Proangiogenic Markers are Associated with Vascular Complications within Ghanaian Sickle Cell Disease Patients 
    Antwi-Boasiako, Charles; Frimpong, Emmanuel; Gyan, Ben; Kyei-Baafour, Eric; Sey, Fredericka; Dzudzor, Bartholomew; Abdul-Rahman, Mubarak; Dankwah, Gifty B.; Otu, Kate H.; Ndanu, Tom A.; Campbell, Andrew D.; Ekem, Ivy; Donkor, Eric S. (Medical Sciences, 2018)
    Sickle cell disease (SCD) is an inherited blood disorder that can result in vasculopathy and end organ damage. Angiogenesis has been implicated as a key contributing factor to vascular mediated tissue injury in SCD. The ...
  • Hematological Parameters in Ghanaian sickle cell disease patient 
    antwi-Boasiako, charles; ekem, ivy; Doku, alfred; Dzudzor, Bartholomew; Dankwah, Gifty B; Otu, Kate hagar; Ahenkorah, John; Aryee, Robert; Sey, Frederika; Abdul-rahman, Mubarak; Ekem, Ivy; Antwi-Boasiako, Charles (Journal of Blood Medicine, 2018)
    Background: Effective treatment and management of sickle cell disease (SCD) has been a challenge in Africa over the years. Hematological parameters are very useful profiles in the effective management of the disease. ...
  • Hematological parameters in Ghanaian sickle cell disease patients 
    Antwi-Boasiako1, Charles; Ekem, Ivy; Mubarak, Abdul-Rahman; Sey, Frederika; Doku, Alfred; Dzudzor, Bartholomew; Dankwah, Gifty B; Otu, Kate Hagar; Ahenkorah, John; Aryee, Robert (2018-09)
    Background: Effective treatment and management of sickle cell disease (SCD) has been a challenge in Africa over the years. Hematological parameters are very useful profiles in the effective management of the disease. ...
  • Hematological parameters in Ghanaian sickle cell disease patients 
    Antwi-Boasiako, Paul; Ekem, Ivy; Abdul-Rahman, Mubarak (2018-04)
    Background: Effective treatment and management of sickle cell disease (SCD) has been a challenge in Africa over the years. Hematological parameters are very useful profiles in the effective management of the disease. ...
  • Levels of Soluble Endothelium Adhesion Molecules and Complications among Sickle Cell Disease Patients in Ghana 
    Antwi-Boasiako, Charles; Donkor, Eric S.; Sey, Fredericka; Dzudzor, Bartholomew; Otu, Kate H; . Dale, Campbell A; Ekem, Ivy (2018-04)
    Abstract: Background: Soluble adhesion molecules are involved in the gathering and joining of inflammatory cells to vascular endothelium. Therefore, they serve as potential markers of endothelial dysfunction in vascular ...
  • Ocular manifestations of sickle cell disease at the Korle-bu Hospital, Accra, Ghana 
    Osafo-Kwaako, Alfred; Kiman, Kahaki; lIako, Dunera; Akafo, Stephen; Ekem, Ivy; Onike, Rodrigues; Enweronu-Laryea, Christabel; Nentwich, Martin M. (2010-10)
    Sickle cell hemoglobinopathies are a group of inherited diseases characterized by an abnormality in the ~-chain of the hemoglobin molecule. Sickle cell disease (SCD) is found all over the world except in the Far East ...
  • Ocular manifestations of sickle cell disease at the Korle-bu Hospital, Accra, Ghana 
    Osafo-Kwaako, Alfred; Kiman, Kahaki; Ilako, Dunera; Akafo, Stephen; Ekem, Ivy; Rodrigues, Onike; Enweronu-Laryea, Christabel; Nentwich, Martin M. (European Journal of Ophthalmology, 2011)
    PurPose. To determine the magnitude and pattern of ocular manifestations in sickle cell disease at Korle-bu Hospital, Accra, Ghana. Methods. Hospital-based cross-sectional study including all patients with sickle cell ...
  • OUTCOME OF CHILDHOOD ACUTE LYMPHOBLASTIC LEUKAEMIA IN A PAEDIATRIC ONCOLOGY UNIT IN GHANA 
    Baeta, Novisi; Segbefia, Catherine; Renner, Lorna; Dei-Adomakoh, Yvonne; Ekem, Ivy (2010-12)
    Worldwide, acute leukaemias account for about a third of all childhood cancers and ALL represents about 80% of all acute leukaemias in children below the age of 15 years [1]. Survival rates for childhood ALL have ...
  • Steroid-induced dysglycaemia in patients with haematological disorders a ten-year review in a tertiary hospital in Ghana 
    Dei-Adomakoh, Yvonne A.; Akpalu, Josephine; Yawson, Alfred E.; Ekem, Ivy; Reynolds, Margaret; Atiase, Yacoba (GHANA MEDICAL JOURNAL, 2019)
    Background: Glucocorticoids (steroids) play a key role in the management of multiple medical conditions including haematological disorders. This study looked at the prevalence of steroid induced dysglycaemia in patients ...
  • A study of the geographic distribution and associated risk factors of leg ulcers within an international cohort of sickle cell disease patients: the CASiRe group analysis 
    Antwi-Boasiako, Charles; Andemariam, Biree; Colombatti, Raffaella; Asare, Eugenia Vicky; Strunk, Crawford; Piccone, Connie M.; Manwani, Deepa; Boruchov, Donna; Farooq, Fatimah; Urbonya, Rebekah; Wilson, Samuel; Boatemaa, Gifty Dankwah; Perrotta, Silverio; Sainati, Laura; Rivers, Angela; Rao, Sudha; Zempsky, William; Ekem, Ivy; Sey, Fredericka; Segbefia, Catherine; Inusa, Baba; Tartaglione, Immacolata; Campbell, Andrew D. (Annals of Hematology, 2020)
    Vasculopathy is a hallmark of sickle cell disease ultimately resulting in chronic end organ damage. Leg ulcer is one of its sequelae, occurring in ~ 5–10% of adult sickle cell patients. The majority of leg ulcer publications ...
  • UK-based real-time lymphoproliferative disorder diagnostic service to improve the management of patients in Ghana 
    Parkins, Elizabeth; Owen, Roger G.; Bedu-Addo, George; Opare Sem, Ohene; Ekem, Ivy; Adomakoh, Yvonne; Bates, Imelda (J Hematopathol, 2009)
    The objective of the study was to evaluate the feasibility of a UK-based real-time service to improve the diagnosis and management of lymphoproliferative disorders (LPDs) in Ghana. Adult patients reporting to hospital with ...