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Evaluation of the efficacy of xylopic acid — artesunate, and xylopic acid —amodiaquine co-administration in plasmodium berghei malaria mouse model

Acheampong Osei, Silas (UCC, 2020-10)

Evidence of Plasmodium resistance to some of the current antimalarial agents makes it imperative to search for newer, and effective drugs to combat this challenge, and combination therapy remains key in the quest to address ...
Quality evaluation of locally manufactured amodiaquine tablets in Accra, Ghana

Owusu-Ansah, E.; Ametepe, O.N.; Boamponsem, L. K.; Asiamah, I.; Addo, J.E Koranteng; Tuffour, J.K. (University of Cape Coast, 2010)

This study was carried out to assess the quality of four brands of locally produced amodiaquine tablets in Accra, Ghana. The assayed samples were characterized for their weight, percentage active ingredients, and percentage ...
Synergism between Pfcrt and Pfmdr1 genes could account for the slow recovery of chloroquine sensitive Plasmodium falciparum strains in Ghana after chloroquine withdrawal

Asare, Kwame K.; Boampong, Johnson N.; Duah, Nancy O.; Afoakwah, Richmond; Sehgal, Rakesh; Quashie, Neils B. (University of Cape Coast, 2015)

Summary Unlike other countries, the chloroquine resistant marker Pfcrt T76 mutant has remained fairly stable in Ghana several years after official disuse of chloroquine. Certain mutations inPfmdr1may potentiate Pfcrt T76, ...
Xylopic Acid-Amodiaquine and Xylopic Acid-Artesunate Combinations are Effective in Managing Malaria in Plasmodium Berghei-infected Mice.

Osei, Silas Acheampong; Biney, Robert Peter; Obese, Ernest; Agbenyeku, Mary Atta-Panyi; Attah, Isaac Yaw; Ameyaw, Elvis Ofori; Boampong, Johnson Nyarko (PubMed, 2021-02)

Background: Evidence of plasmodium resistance to some of the current antimalarial agents makes it imperative to search for newer and effective drugs to combat malaria. Therefore, this study evaluated whether the ...
Xylopic Acid-Amodiaquine and Xylopic Acid-Artesunate Combinations are Effective in Managing Malaria in Plasmodium Berghei-infected Mice.

Osei, Silas Acheampong; Biney, Robert Peter; Obese, Ernest; Agbenyeku, Mary Atta-Panyi; Attah, Isaac Yaw; Ameyaw, Elvis Ofori; Boampong, Johnson Nyarko (2020)

Background: Evidence of plasmodium resistance to some of the current antimalarial agents makes it imperative to search for newer and effective drugs to combat malaria. Therefore, this study evaluated whether the ...

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