Browsing COLLEGE OF AGRICULTURAL & NATURAL SCIENCES by Author "Mann, John"

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A novel inhibitor of human telomerase derived from 10h-indolo[3,2-b]quinoline

Caprio, Vittorio; Guyen, Berengere; Opoku-Boahen, Yaw; Mann, John; Gowan, Sharon M.; Kelland, Lloyd M.; Readd, Martin A.; Neidle, Stephen (University of Cape Coast, 2000)

The bis-dimethylaminoethyl derivative of quindoline (10H-indolo[3,2-b]quinoline), an alkaloid from the West African shrub Cryptolepis sanguinolenta, has been synthesised. This has been shown to have modest cytotoxicity, ...
Synthesis and evaluation of quindoline and its analogue as potential anticancer agents

Boahen, Yaw Opoku; Mann, John (University of Cape Coast, 2014)

Several derivatives of quindoline, 10H-(indolo[3,2-b]quinoline), alkaloids were prepared by the modification of the Pfitzinger quinoline reaction. The conversion of quindoline was 71% while that of another compound, ...

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