Background: Patients with Sickle Cell Disease (SCD) have acute pain episodes that vary between patients. We examined whether differences exist in socio-demographic profiles, blood indices and pain attributed fear of movement ...

Sickle cell hemoglobinopathies are a group of inherited diseases characterized by an abnormality in the β-chain of the hemoglobin molecule. Sickle cell disease (SCD) is found all over the world except in the Far East ...

Abstract: Background: Soluble adhesion molecules are involved in the gathering and joining of inflammatory cells to vascular endothelium. Therefore, they serve as potential markers of endothelial dysfunction in vascular ...

Background: Effective treatment and management of sickle cell disease (SCD) has been a challenge in Africa over the years. Hematological parameters are very useful profiles in the effective management of the disease. ...

Abstract: Sickle cell disease (SCD) is an inherited blood disorder that can result in vasculopathy and end organ damage. Angiogenesis has been implicated as a key contributing factor to vascular mediated tissue injury ...

Abstract: Endothelial nitric oxide synthase (eNOS) variants have been found to be associated with several vascular disorders as well as the pathogenesis of sickle cell disease (SCD) complications such as vaso-occlusive ...

Background: Anemia is defined as a reduction in the hemoglobin concentration of blood, which consequently reduces the oxygen-carrying capacity of red blood cells such that they are unable to meet the body’s physiological needs. ...

BACKGROUND: Anaemia is considered a severe public health problem by WHO and is seen as such in Ghana. Its prevalence in pregnancy has remained high despite improved antenatal care. The main purpose of this study was to ...

Abstract The objective of the study was to evaluate the feasibility of a UK-based real-time service to improve the diagnosis and management of lymphoproliferative disorders (LPDs) in Ghana. Adult patients reporting to ...

Background: Kidney diseases have emerged as significant cause of morbidity and mortality in HIV subject on antiretroviral therapy (ART). In Ghana, routine follow up of HIV positive clients is by estimation of serum ...