SICKLE CELL DISEASE: REAPPRAISAL OF THE ROLE OF FOETAL HAEMOGLOBIN LEVELS IN THE FREQUENCY OF VASO-OCCLUSIVE CRISIS

ANTWI-BOASIAKO, C.; FRIMPONG, E.; ABABIO, G. K.; DZUDZOR2, B.; EKEM, I.; ANTWI, D. A.; SODZI-TETTEY, N.A

dc.contributor.author	ANTWI-BOASIAKO, C.
dc.contributor.author	FRIMPONG, E.
dc.contributor.author	ABABIO, G. K.
dc.contributor.author	DZUDZOR2, B.
dc.contributor.author	EKEM, I.
dc.contributor.author	ANTWI, D. A.
dc.contributor.author	SODZI-TETTEY, N.A
dc.date.accessioned	2021-03-26T10:45:34Z
dc.date.available	2021-03-26T10:45:34Z
dc.date.issued	2015-06
dc.identifier.uri	http://hdl.handle.net/123456789/5184
dc.description.abstract	Background: Foetal haemoglobin has been implicated in the modulation of sickle cell crisis. Its level is generally inversely proportional to the severity of sickle cell disease (SCD) for a given sickle cell phenotypes. The main aim of therapy for vaso-occlusive crisis (VOC), which is the hallmark of SCD, is to reduce the chances of sickling through the prevention of polymerization of HbS. One way of preventing this polymerization is by increasing foetal haemoglobin levels.	en_US
dc.language.iso	en	en_US
dc.subject	Haemoglobin F	en_US
dc.subject	Frequency of crisis	en_US
dc.subject	sickle cell disease	en_US
dc.title	SICKLE CELL DISEASE: REAPPRAISAL OF THE ROLE OF FOETAL HAEMOGLOBIN LEVELS IN THE FREQUENCY OF VASO-OCCLUSIVE CRISIS	en_US
dc.type	Article	en_US