ANTI-INFLAMMATORY AND ANTIMICROBIAL ACTIVITIES OF HIPPOCRATEA INDICA ROOT BARK AND POGA OLEOSA FRUITS

Ogbole, O. O.; Ekor, M. N.; Oluremi, B. B.; Ajaiyeoba, E. O.; Ayoola, M. A.

dc.contributor.author	Ogbole, O. O.
dc.contributor.author	Ekor, M. N.
dc.contributor.author	Oluremi, B. B.
dc.contributor.author	Ajaiyeoba, E. O.
dc.contributor.author	Ayoola, M. A.
dc.date.accessioned	2021-04-14T12:34:08Z
dc.date.available	2021-04-14T12:34:08Z
dc.date.issued	2007-03
dc.identifier.uri	http://hdl.handle.net/123456789/5341
dc.description.abstract	Abstract The methanolic extracts of Hippocratea indica root bark and Poga oleosa fruits were investigated for anti-inflammatory and antimicrobial activities. Both extracts inhibited carrageenan-induced paw oedema significantly in rats in a dose-dependent manner in 4 h. H. indica inhibited oedema significantly at the minimal dose (125 mg/ml, p< 0.05) from 2 h onward, and gave 100% inhibition in 4 h. at 250 mg/kg. It was shown to be a more potent anti-inflammatory agent than P. oleosa. Also, H. indica extract exhibited greater antimicrobial activity against tested bacteria, with Staphylococcus aureus being the most susceptible bacterium (MIC, 16 mg/ml). Both plants were inactive against Candida albicans. These results confirm the anti-inflammatory and antibacterial activities of the two plants.	en_US
dc.language.iso	en	en_US
dc.subject	Hippocratea indica	en_US
dc.subject	Poga oleosa	en_US
dc.subject	anti-inflammatory	en_US
dc.subject	antimicrobial	en_US
dc.title	ANTI-INFLAMMATORY AND ANTIMICROBIAL ACTIVITIES OF HIPPOCRATEA INDICA ROOT BARK AND POGA OLEOSA FRUITS	en_US
dc.type	Article	en_US