ISOLATION OF ent-LABDANE (+)-12,15-EPOXYLABDA-8(17), 12,14-TRIEN-16-YL ACETATE FROM THE SEEDS OF Turraeanthus africanus AND ITS CYTOSTATIC/CYTOTOXIC EFFECT ON THE GROWTH OF CANCER CELLS in vitro

Tayman, F. S.; Barku, V. Y. Atsu; Opoku-Boahen, Y.; Seifert, K.; Grote, D.

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ISOLATION OF ent-LABDANE (+)-12,15-EPOXYLABDA-8(17), 12,14-TRIEN-16-YL ACETATE FROM THE SEEDS OF Turraeanthus africanus AND ITS CYTOSTATIC/CYTOTOXIC EFFECT ON THE GROWTH OF CANCER CELLS in vitro

Tayman, F. S.; Barku, V. Y. Atsu; Opoku-Boahen, Y.; Seifert, K.; Grote, D.

URI: http://hdl.handle.net/123456789/5751

Date: 2006

Abstract:

(+)-12,15-Epoxylabda-8(17),12,14-trien-16-yl acetate has been isolated from the seed kernels of Turraeanthus africanus (Nelw. ex DC). The stereo structure was confirmed by 1D- and 2D-NMR spectroscopy. Cytostatic/cytotoxic test of (I) on the growth of cancer cells in vitro gave positive results