Browsing COLLEGE OF HEALTH & ALLIED SCIENCES by Author "Ghansah, Anita"

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Computational/in silico methods in drug target and lead prediction

Agamah, Francis E.; Mazandu, Gaston K.; Hassan, Radia; Bope, Christian D.; Thomford, Nicholas E.; Ghansah, Anita; Chimusa, Emile R. (Briefings in Bioinformatics, 2020)

Drug-like compounds are most of the time denied approval and use owing to the unexpected clinical side effects and cross-reactivity observed during clinical trials. These unexpected outcomes resulting in significant ...
Computational/in silico methods in drug target and lead prediction

Agamah, Francis E.; Mazandu, Gaston K.; Hassan, Radia; Bope, Christian D.; Thomford, Nicholas E.; Ghansah, Anita; Chimusa, Emile R. (Briefings in Bioinformatics, 2020)

Drug-like compounds are most of the time denied approval and use owing to the unexpected clinical side effects and cross-reactivity observed during clinical trials. These unexpected outcomes resulting in significant ...
Inducible nitric oxide synthase 2 promoter polymorphism and malaria disease severity in children in Southern Ghana

Dzodzomenyo, Mawuli; Ghansah, Anita; Ensaw, Nana; Dovie, Benjamin; Bimi, Langbong; Quansah, Reginald; Gyan, Ben A.; Gyakobo, Mawuli; Amoani, Benjamin (PLOS ONE, 2018)

Objective We assessed the association of mutant allele frequencies of nitric oxide synthase 2 (NOS2) gene at two SNPs (-954 and -1173) with malaria disease severity in children from a malaria endemic area in Southern ...

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