University of Cape Coast Institutional Repository

Browsing COLLEGE OF HEALTH & ALLIED SCIENCES by Author "Rowe, Arielle"

Browsing COLLEGE OF HEALTH & ALLIED SCIENCES by Author "Rowe, Arielle"

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  • African Lettuce (Launaea taraxacifolia) Displays Possible Anticancer Effects and Herb–Drug Interaction Potential by CYP1A2, CYP2C9, and CYP2C19 Inhibition 
    Thomford, Nicholas E.; Mkhize, Buyisile; Dzobo, Kevin; Mpye, Keleabetswe; Rowe, Arielle; Parker, M. Iqbal; Wonkam, Ambroise; Skelton, Michelle; September, Alison V (OMICS A Journal of Integrative Biology, 2016)
    Medicinal plants are part of the healthcare systems worldwide, especially in low- and middle-income countries. African lettuce (Launaea taraxacifolia) is cultivated extensively in Africa, from Senegal in the west to ...
  • Chemoresistance to Cancer Treatment: Benzo-α-Pyrene as Friend or Foe? 
    Dzobo, Kevin; Hassen, Naseeha; Senthebane, Dimakatso Alice; Thomford, Nicholas Ekow; Rowe, Arielle; Shipanga, Hendrina; Wonkam, Ambroise; Parker, M. Iqbal; Mowla, Shaheen; Dandara, Collet (Molecules, 2018-04-17)
    Abstract: Background: Environmental pollution such as exposure to pro-carcinogens including benzo-α-pyrene is becoming a major problem globally. Moreover, the effects of benzo-α-pyrene (BaP) on drug pharmacokinetics, ...
  • Fibroblast-Derived Extracellular Matrix Induces Chondrogenic Differentiation in Human Adipose-Derived Mesenchymal Stromal/Stem Cells in Vitro 
    Dzobo, Kevin; Turnley, Taegyn; Wishart, Andrew; Rowe, Arielle; Kallmeyer, Karlien; van Vollenstee, Fiona A.; Thomford, Nicholas E.; Dandara, Collet; Chopera, Denis; Pepper, Michael S.; Parker, M. Iqbal (International Journal of Molecular Sciences, 2016-08-03)
    Mesenchymal stromal/stem cells (MSCs) represent an area being intensively researched for tissue engineering and regenerative medicine applications. MSCs may provide the opportunity to treat diseases and injuries that ...
  • Natural Products for Drug Discovery in the 21st Century: Innovations for Novel Drug Discovery 
    Thomford, Nicholas Ekow; Senthebane, Dimakatso Alice; Rowe, Arielle; Munro, Daniella; Seele, Palesa; Maroyi, Alfred (International Journal of Molecular Sciences, 2018-05-25)
    The therapeutic properties of plants have been recognised since time immemorial. Many pathological conditions have been treated using plant-derived medicines. These medicines are used as concoctions or concentrated plant ...
  • Not Everyone Fits the Mold: Intratumor and Intertumor Heterogeneity and Innovative Cancer Drug Design and Development 
    Dzobo, Kevin; Senthebane, Dimakatso Alice; Thomford, Nicholas Ekow; Rowe, Arielle; Dandara, Collet; Parker, M. Iqbal (OMICS A Journal of Integrative Biology, 2018)
    Disruptive innovations in medicine are game-changing in nature and bring about radical shifts in the way we un- derstand human diseases, their treatment, and/or prevention. Yet, disruptive innovations in cancer drug design ...
  • The Role of Tumor Microenvironment in Chemoresistance: To Survive, Keep Your Enemies Closer 
    Senthebane, Dimakatso Alice; Rowe, Arielle; Thomford, Nicholas Ekow; Shipanga, Hendrina; Munro, Daniella; Al Mazeedi, Mohammad A. M.; Almazyadi, Hashim A. M.; Kallmeyer, Karlien; Dandara, Collet; Pepper, Michael S.; Parker, M. Iqbal; Dzobo, Kevin (International Journal of Molecular Sciences, 2017-07-21)
    Chemoresistance is a leading cause of morbidity and mortality in cancer and it continues to be a challenge in cancer treatment. Chemoresistance is influenced by genetic and epigenetic alterations which affect drug uptake, ...

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