University of Cape Coast Institutional Repository

Browsing School of Medical Sciences by Author "Obiri, David D."

Browsing School of Medical Sciences by Author "Obiri, David D."

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  • Allergic Airway-Induced Hypersensitivity Is Attenuated by Bergapten in Murine Models of Inflammation 
    Aidoo, Douglas B.; Obiri, David D.; Osafo, Newman; Antwi, Aaron O.; Essel, Leslie B.; Duduyemi, Babatunde M.; Ekor, Martins (Advances in Pharmacological Sciences, 2019)
    Bergapten (5-methoxypsoralen, 5-MOP) is a plant-derived furocoumarin with demonstrated anti-inflammatory action. *e present study investigated its effects on allergic inflammation in two related pathways of mast cell ...
  • Aqueous Ethanol Fruit Extract of Xylopia aethiopica and Xylopic Acid Exhibit Antiinflammatory Activity Through Inhibition of the Arachidonic Acid Pathway 
    Osafo, Newman; Biney, Robert P.; Obiri, David D. (UK Journal of Pharmaceutical and Biosciences, 2016)
    In the form of a decoction, X. aethiopica is traditionally employed in the treatment of bronchitis, asthma, arthritis and rheumatism in Ghana, Nigeria and Cameroon. This study establishes the inhibitory effect of X. ...
  • Bergapten modulates ovalbumin-induced asthma 
    Adakudugu, Emmanuel A.; Obiri, David D.; Ameyaw, Elvis O.; Obese, Ernest; Biney, Robert P.; Aidoo, Douglas B.; Henneh, Isaac T.; Oge, Elizabeth N.; Thomford, Ama K.; Adanusa, Madison (Scientific African, 2020)
    Prior studies on the anti-inflammatory compound bergapten have shown promise in averting allergic airway hyperresponsiveness. This study sought to establish its possible role in modulating an immunologically-induced airway ...
  • Protective effect of bergapten in acetic acid-induced colitis in rats 
    Adakudugu, Emmanuel A.; Ameyaw, Elvis O.; Obese, Ernest; Biney, Robert P.; Henneh, Isaac T.; Aidoo, Douglas B.; Oge, Elizabeth N.; Attah, Isaac Y.; Obiri, David D. (Heliyon, 2020)
    Bergapten (5-methoxysporalen) is a furanocoumarin extracted from several species of citrus and bergamot oil. Bergamot essential oil is used traditionally in the management of inflammatory conditions. Previous studies on ...

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