University of Cape Coast Institutional Repository

Browsing School of Medical Sciences by Subject "Malaria"

Browsing School of Medical Sciences by Subject "Malaria"

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  • Fc/R IIA polymorphism -131H/R and malaria severity in Ghanaian children 
    Amoako-Sakyi, D. (International Congress on Infectious Diseases, 2012)
    Plasmodium falciparum malaria still remains a major public health problem in most parts of the world especially in Sub Saharan Africa. Pathogenesis of severe malaria is still not fully understood and several factors have ...
  • Identification of Plasmodium falciparum circumsporozoite protein-specific CD8+ T cell epitopes in a malaria exposed population 
    Kusi, Kwadwo A.; Aggor, Felix E.; Amoah, Linda E.; Anum, Dorothy; Nartey, Yvonne; Amoako-Sakyi, Daniel; Obiri-Yeboah, Dorcas; Hollingdale, Michael; Ganeshan, Harini; Belmonte, Maria; Peters, Bjoern; Kim, Yohan; Tetteh, John; Kyei-Baafour, Eric; Dodoo, Daniel; Villasante, Eileen; Sedegah, Martha (PLoS ONE, 2020)
    Background Sterile protection against malaria, most likely mediated by parasite-specific CD8+ T cells, has been achieved by attenuated sporozoite vaccination of animals as well as malaria-naïve and malaria-exposed subjects. ...
  • Isobolographic analysis of co-administration of two plant-derived antiplasmodial drug candidates, cryptolepine and xylopic acid, in Plasmodium berghei 
    Ameyaw, Elvis O.; Asmah, Kodwo B.; Biney, Robert P.; Henneh, Isaac T.; Owusu‑Agyei, Phyllis; Prah, James; Forkuo, Arnold D. (Malaria Journal, 2018)
    Background: Increasing resistance to current anti malarial therapies requires a renewed effort in searching for alternative therapies to combat this challenge, and combination therapy is the preferred approach to address ...
  • Prevalence, genetic variants and clinical implications of G-6-PD deficiency in Burkina Faso: a systematic review 
    Ouattara, Abdoul Karim; Yameogo, Pouiré; Traore, Lassina; Diarra, Birama; Assih, Maléki; Compaore, Tegwindé Rébéca; Obiri-yeboah, Dorcas; Soubeiga, Serge Théophile; Djigma, Florencia Wendkuuni; Simpore, Jacques (BMC Medical Genetics, 2017)
    Background: It is now well-known that some antimalarials such as primaquine may induce severe hemolytic anemia in people with G-6-PD deficiency. Antimalarial drug prescriptions must, therefore take into account the patient’s ...
  • A STAT6 Intronic Single-Nucleotide Polymorphism is Associated with Clinical Malaria in Ghanaian Children 
    Amoako-sakyi, Daniel; Adukpo, selorme; Kusi, Kwadwo A.; Dodoo, Daniel; Ofori, Michael F.; Adjei, George O.; Edoh, Dominic E.; Asmah, Richard H.; Adu, Bright; Brown, Charles; Obiri-Yeboah, Dorcas; Futagbi, Godfred; Abubakari, sharif Buari; troye-Blomberg, Marita; Akanmori, Bartholomew D.; Goka, Bamenla Q.; Arko-Mensah, John; Gyan, Ben A. (Genetics & Epigenetics, 2016)
    Malaria pathogenesis may be influenced by IgE responses and cytokine cross-regulation. Several mutations in the IL-4/STAT6 signaling pathway can alter cytokine cross-regulation and IgE responses during a Plasmodium falciparum ...

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