APOBEC3G expression and HIV-1 infection in Burkina Faso

Compaor, Tegwinde Rebeca; Soubeiga, Serge Theophile; Ouattara, Abdoul Karim; Tchelougou, Damehan; Bisseye, Cyrille; Bakouan, Didier Romuald; Compaore, Issaka; Dembele, Augustine; Yonli, Albert Theophane; Obiri-Yeboah, Dorcas; Djigma, Wendkuuni Florencia; Simpore, Jacques

dc.contributor.author	Compaor, Tegwinde Rebeca
dc.contributor.author	Soubeiga, Serge Theophile
dc.contributor.author	Ouattara, Abdoul Karim
dc.contributor.author	Tchelougou, Damehan
dc.contributor.author	Bisseye, Cyrille
dc.contributor.author	Bakouan, Didier Romuald
dc.contributor.author	Compaore, Issaka
dc.contributor.author	Dembele, Augustine
dc.contributor.author	Yonli, Albert Theophane
dc.contributor.author	Obiri-Yeboah, Dorcas
dc.contributor.author	Djigma, Wendkuuni Florencia
dc.contributor.author	Simpore, Jacques
dc.date.accessioned	2023-10-17T14:50:39Z
dc.date.available	2023-10-17T14:50:39Z
dc.date.issued	2018
dc.identifier.uri	http://hdl.handle.net/123456789/9560
dc.description.abstract	APOBEC3G is a potent inhibitor of HIV-1 replication, and act by deaminating cytidines in uracil on the negative strand of the viral cDNA. In this case-control study, APOBEC3G expression in subjects’ naïve to HAART infected by HIV-1 and the effect of APOBEC3G polymorphism on its expression were evaluated. The results show that the HIV-1 infected carriers of the G minor alleles of the variant rs8177832 had a higher expression of APOBEC3G mRNA than the controls carriers of the G minor allele. APOBEC3G polymorphisms could play an important role in the modulation of the HIV-1 dissemination	en_US
dc.language.iso	en	en_US
dc.publisher	Journal of Public Health in Africa	en_US
dc.subject	HIV-1	en_US
dc.subject	APOBEC3G mRNA	en_US
dc.subject	rs8177832	en_US
dc.subject	rs35228531	en_US
dc.subject	rs6001417	en_US
dc.subject	Burkina Faso.	en_US
dc.title	APOBEC3G expression and HIV-1 infection in Burkina Faso	en_US
dc.type	Article	en_US