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ANTI-INFLAMMATORY AND ANTIMICROBIAL ACTIVITIES OF HIPPOCRATEA INDICA ROOT BARK AND POGA OLEOSA FRUITS

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dc.contributor.author Ogbole, O. O.
dc.contributor.author Ekor, M. N.
dc.contributor.author Oluremi, B. B.
dc.contributor.author Ajaiyeoba, E. O.
dc.contributor.author Gbolade, A. A.
dc.contributor.author Ayoola, M. A.
dc.contributor.author Adeyemi, A. A.
dc.date.accessioned 2023-10-20T11:49:05Z
dc.date.available 2023-10-20T11:49:05Z
dc.date.issued 2007
dc.identifier.issn 0189-6016©2007
dc.identifier.uri http://hdl.handle.net/123456789/9775
dc.description.abstract The methanolic extracts of Hippocratea indica root bark and Poga oleosa fruits were investigated for anti-inflammatory and antimicrobial activities. Both extracts inhibited carrageenan-induced paw oedema significantly in rats in a dose-dependent manner in 4 h. H. indica inhibited oedema significantly at the minimal dose (125 mg/ml, p< 0.05) from 2 h onward, and gave 100% inhibition in 4 h. at 250 mg/kg. It was shown to be a more potent anti-inflammatory agent than P. oleosa. Also, H. indica extract exhibited greater antimicrobial activity against tested bacteria, with Staphylococcus aureus being the most susceptible bacterium (MIC, 16 mg/ml). Both plants were inactive against Candida albicans. These results confirm the anti-inflammatory and antibacterial activities of the two plants. en_US
dc.language.iso en en_US
dc.publisher African Journal of Traditional, Complementary and Alternative Medicines en_US
dc.subject Hippocratea indica en_US
dc.subject Poga oleosa en_US
dc.subject Anti-inflammatory en_US
dc.subject antimicrobial en_US
dc.title ANTI-INFLAMMATORY AND ANTIMICROBIAL ACTIVITIES OF HIPPOCRATEA INDICA ROOT BARK AND POGA OLEOSA FRUITS en_US
dc.type Article en_US


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