dc.description.abstract |
Urinary tract infection (UTI) in pregnancy is associated with significant morbidity for
both the mother and the baby. Proper investigation and prompt treatment are needed to prevent
the serious life-threatening condition and morbidity associated with UTI in pregnant women.
Aim: This study was designed to detect common uropathogens and their antibiotic susceptibility
pattern among asymptomatic pregnant women attending antenatal care in the Bolgatanga Regional
Hospital.
Methodology: Mid-stream urine samples were collected from 200 individuals and inoculated onto
cysteine lactose electrolyte deficient (CLED) agar media. Colony counts yielding bacterial growth
of ≥ 105 CFU /ml was regarded as significant bacteriuria. Pure isolates of bacterial pathogens were
characterized by colony morphology, Gram-stain and standard biochemical procedures. Kirby Bauer disc diffusion method was used for antimicrobial susceptibility testing of all identified isolates.
Results: The overall prevalence of bacteria-associated asymptomatic UTI was 17.5%. Escherichia
coli (42.9%) was the most isolated organism followed by Staphylococcus aureus (34.3%),
Klebsiella pneumoniae (11.4%), Staphylococcus saprophyticoccus (5.7%) and Proteus mirabilis 2
(5.7%). Yeast cells and Schistosoma haematobium were also recorded in 2% of the women.
Isolates showed significant sensitivity to commercially prepared antibiotic discs. However, higher
level of resistance was recorded with tetracycline, nitrofurantoin and nalidixic acid.
Conclusion: Early screening for UTI should be done for all pregnant women and those found to be
infected need to be treated with appropriate antimicrobial agents to avoid complications. |
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