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Costus afer: A Systematic Review of Evidence-Based Data in support of Its Medicinal Relevance

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dc.contributor.author Boison, Daniel
dc.contributor.author Adinortey, Cynthia Ayefoumi
dc.contributor.author Babanyinah, Godwin Kweku
dc.contributor.author Quasie, Olga
dc.contributor.author Agbeko, Rosemary
dc.contributor.author Wiabo-Asabil, Gilbert Kofi
dc.contributor.author Adinortey, Michael Buenor
dc.date.accessioned 2023-09-29T12:28:30Z
dc.date.available 2023-09-29T12:28:30Z
dc.date.issued 2019
dc.identifier.uri http://hdl.handle.net/123456789/8698
dc.description.abstract Costus afer (C. afer) is a plant commonly known as ginger lily, spiral ginger, or bush cane. It is reportedly used in traditional medicine practice (TMP) to treat and manage many ailments including diabetes mellitus, stomach ache, arthritis, inflammation, and gout. These purported ethnomedicinal uses have triggered many research studies on the plant to amass scientific evidence. However, these research reports are scattered, and thus, this systematic review seeks to provide a comprehensive update on it covering its traditional uses, phytochemical and nutritional constituents, pharmacological activities, and toxicological effects. An online search was done using search engines such as Google Scholar, PubMed, and ScienceDirect from the period 1970 to 2019. The online search included the use of keywords, “Costus afer Ker-Gawl” or “Costus afer.” The search revealed that the stem and leaves of the plant contain substantial amounts of micronutrients and macronutrients. The leaves, stem, rhizomes, and roots of C. afer contain several steroidal sapogenins, aferosides, dioscin, and paryphyllin C and flavonoid glycoside kaempferol-3-O-α-L- rhamnopyranoside. Experimental studies on various parts of the plant showed bioactivities such as antihyperglycemic, hepa- tocellular protection, cardioprotection, nephroprotection, testicular protection, CNS depressant, analgesic, antiarthritis, anti- bacterial, and antioxidant. Based on these evident data, it is concluded that the plant could be used as an alternative and complementary therapy for many oxidative stress-related diseases, provided further scientific studies on the toxicological and pharmacological aspects are carried out. en_US
dc.language.iso en en_US
dc.publisher University of Cape Coast en_US
dc.title Costus afer: A Systematic Review of Evidence-Based Data in support of Its Medicinal Relevance en_US
dc.type Article en_US


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