University of Cape Coast Institutional Repository

Browsing School of Allied Health Sciences by Subject "genomics"

Browsing School of Allied Health Sciences by Subject "genomics"

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  • Computational/in silico methods in drug target and lead prediction 
    Agamah, Francis E.; Mazandu, Gaston K.; Hassan, Radia; Bope, Christian D.; Thomford, Nicholas E.; Ghansah, Anita; Chimusa, Emile R. (Briefings in Bioinformatics, 2020)
    Drug-like compounds are most of the time denied approval and use owing to the unexpected clinical side effects and cross-reactivity observed during clinical trials. These unexpected outcomes resulting in significant ...
  • Computational/in silico methods in drug target and lead prediction 
    Agamah, Francis E.; Mazandu, Gaston K.; Hassan, Radia; Bope, Christian D.; Thomford, Nicholas E.; Ghansah, Anita; Chimusa, Emile R. (Briefings in Bioinformatics, 2020)
    Drug-like compounds are most of the time denied approval and use owing to the unexpected clinical side effects and cross-reactivity observed during clinical trials. These unexpected outcomes resulting in significant ...
  • Genomics and Epigenomics of Congenital Heart Defects: Expert Review and Lessons Learned in Africa 
    Thomford, Nicholas Ekow; Dzobo, Kevin; Yao, Nana Akyaa; Chimusa, Emile; Evans, Jonathan; Okai, Emmanuel; Kruszka, Paul; Muenke, Maximilian; Awandare, Gordon; Wonkam, Ambroise (OMICS A Journal of Integrative Biology, 2018)
    Congenital heart defects (CHD) are structural malformations found at birth with a prevalence of 1%. The clinical trajectory of CHD is highly variable and thus in need of robust diagnostics and therapeutics. Major surgical ...

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