Malaria parasite, Plasmodium falciparum, uses haemoglobin in host red blood cells (RBCs) as a major source of nutrient in ring and trophozoite stages. This brings about changes in the morphology and functional characteristics ...

The roots of Jatropha curcas are used traditionally to treat pain. The present study evaluated the analgesic property of ethanolic extract of Jatropha curcas (JAT) in acute and chronic muscle pain models. Acute muscle ...

Background: After years of disuse of chloroquine (CQ) as first-line anti-malarial drug in Ghana, reports from molecular studies conducted in parts of the country indicate varying prevalence of T76 mutation in the pfcrt ...

During chick embryo development, the liquid crystals appear in more than 20 organs at certain developmental stages, and vanish in early post-natal stage. In this study, we found a complex in embryo, the YS-J/I tunnel ...

Current treatment for HIV-1 largely relies on chemotherapy through the administration of antiretroviral drugs. While the search for anti-HIV-1 vaccine remain elusive, the use of highly active antiretroviral therapies ...

Thalassemia and sickle cell disease constitute the most monogenic hemoglobin (Hb) disorders worldwide. Clinical symptoms of a+-thalassemia (a+-thal) are related to inadequate Hb production and accumulation of b- and/or ...

Poor lipid and glucose regulation increases the risk for the development of major cardiovascular diseases and other organ damage. The study evaluated the serum glucose and lipid lowering effects of the 70% ( v/v) ...

Arthritic pain and disability are at or near the top of the list of reasons adult patients seek medical attention. This study therefore attempts to establish the efficacy of an aqueous and ethanolic leaf extract of Pistia ...

Efforts have been intensified to search for more effective antimalarial agents because of the observed failure of some artemisinin- based combination therapy (ACT) treatments of malaria in Ghana. Xylopic acid, a pure ...

Background: Toxoplasma gondii is an obligate, intracellular, apicomplexan parasite that causes toxoplasmosis. Although the global prevalence of toxoplasmosis has been estimated to be approximately 30%, there is limited ...