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Prevalence of intermittent preventive treatment with sulphadoxine-pyrimethamine (IPTp-SP) use during pregnancy and other associated factors in Sekondi-Takoradi, Ghana

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dc.contributor.author Orish, Verner N.
dc.contributor.author Onyeabor, Onyekachi S.
dc.contributor.author Boampong, Johnson N.
dc.contributor.author Afoakwah, Richmond
dc.contributor.author Nwaefuna, Ekene
dc.contributor.author Acquah, Samuel
dc.contributor.author Sanyaolu, Adekunle O.
dc.contributor.author Iriemenam, Nnaemeka C.
dc.date.accessioned 2023-10-03T16:29:27Z
dc.date.available 2023-10-03T16:29:27Z
dc.date.issued 2015-12-04
dc.identifier.uri http://hdl.handle.net/123456789/8951
dc.description.abstract Background: Intermittent preventive treatment in pregnancy (IPTp) with sulphadoxine-pyrimethamine (SP) has been adopted as policy by most countries in sub-Saharan Africa. This cross-sectional study assessed the prevalence of IPTp-SP usage for prevention of malaria among pregnant women as well as evaluated factors associated with IPTp-SP use during pregnancy in Sekondi-Takoradi region of Ghana. Methods: Pregnant women attending their antenatal-care with either clinical/ultrasound evidence of pregnancy were re- cruited. Venous blood was screened for malaria using RAPID response antibody kit and Giemsa staining. Haemoglobin esti- mations were done by cyanmethemoglobin method while Human Immunodeficiency Virus (HIV) screening was performed by the national diagnostic algorithm of two rapid antibody test and western blot confirmation. Results: Of the 754 consented pregnant women interviewed in this study, 57.8% had received IPTp-SP while 42.2% had not at their first contact with the study personnel. Furthermore, 18.6% (81/436) of those that received IPTp-SP were ma- laria positive while 81.4% (355/436) were malaria negative. The results also indicated that 47.7% (51/107) of the pregnant women in their third trimester who were meant to have received at least two-doses of SP had received ≥2 doses while 35.5% (38/107) had received 1 dose. In multivariable logistic regression analysis, pregnant women in their third trimester who re- ceived ≥2 doses of SP showed decreased likelihoods of malaria (adjusted OR, 0.042; 95% CI, 0.003-0.51; P = 0.013). Conclusion: IPTp-SP usage among pregnant women in Sekondi-Takoradi reduces malaria and its use for malaria prevention should be strengthened with proper dosage completion and coverage. en_US
dc.language.iso en en_US
dc.subject Malaria in pregnancy en_US
dc.subject IPTp-SP, en_US
dc.subject anaemia, en_US
dc.subject Ghana en_US
dc.title Prevalence of intermittent preventive treatment with sulphadoxine-pyrimethamine (IPTp-SP) use during pregnancy and other associated factors in Sekondi-Takoradi, Ghana en_US
dc.type Article en_US


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