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Prevalence of helicobacter pylori infection among children living in a rural setting in Sub-Saharan Africa

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dc.contributor.author Awuku, Yaw Asante
dc.contributor.author Simpong, David Larbi
dc.contributor.author Alhassan, Ishmael Kunateh
dc.contributor.author Tuoyire, Derek Anamaale
dc.contributor.author Afaa, Taiba
dc.contributor.author Adu, Patrick
dc.date.accessioned 2023-10-11T13:43:06Z
dc.date.available 2023-10-11T13:43:06Z
dc.date.issued 2017
dc.identifier.uri http://hdl.handle.net/123456789/9265
dc.description.abstract Background: Helicobacter pylori infection affects more than half of the world’s population. It is generally acquired during childhood with no symptoms but has long- term clinical sequelae. This study estimated the prevalence of H. pylori infection amongst children in a rural environment in Africa. Methods: We conducted a cross-sectional study over a four (4)-month period within two rural communities. 240 asymptomatic children were tested using lateral flow immunochromatographic assay for the qualitative detection of H. pylori antigen in a fecal specimen. Statistical analysis and processing was done using Stata version 11. Results: The mean age of the participants was 10.5 ± 2.7 years with the predominant age range being 8–10 years (34.6%), and a mean household size of 7.1 ± 1.7. The study population showed a female preponderance of 57.1%. 88% of the H. pylori positive children lacked pipe and borehole drinking water. All of the positive H. pylori children practiced open-air defecation. The overall prevalence of H. pylori infection among children in this study was at least 14.2%. Conclusion: Our study demonstrated a high prevalence of H. pylori infection among children in a rural setting. Educational status of parents did not affect H. pylori prevalence but increasing household numbers, female gender, source of drinking water other than pipe and borehole, open-air defecation and younger age were associated with a higher H. pylori prevalence. en_US
dc.language.iso en en_US
dc.publisher BMC Public Health en_US
dc.subject H.pylori infection, en_US
dc.subject Prevalence, en_US
dc.subject Immune chromatographic assay, en_US
dc.subject Children en_US
dc.subject Ghana en_US
dc.title Prevalence of helicobacter pylori infection among children living in a rural setting in Sub-Saharan Africa en_US
dc.type Article en_US


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