Vascular endothelial growth factor (VEGF) is one of the most significant mediators of angiogenesis, which interacts with a specific membrane receptor: VEGF receptor 2 (VEGFR2). Studies elsewhere have shown that, a VEGF-blocker ...

Background: Calcium phosphate mediated transfection has been used for delivering DNA into mammalian cells in excess of 30 years due to its most low cost for introducing recombi- nant DNA into culture cells. However, ...

The recently identified novel coronavirus (CoV), the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), causes the coronavirus disease 2019 (COVID-19). While published data about other highly infectious human ...

Endurance exercise is an effective therapeutic inter- vention with substantial pro-healthspan effects. Male Drosophila respond to a ramped daily program of exercise by inducing conserved physiological re- sponses similar ...

One of the immunosurveillance mechanisms of the immune system is the expression of Major Histocompatibility Complex class I-related chain molecules A and B (MIC-A and B) on tumor cell surface. MIC-A and B are the ligands of ...

Background T cell cytokines play important roles in the development and progression of rheumatoid arthritis (RA). Loss of Th1/Th2 and Th17/Treg balance has been reported in several in ammatory autoimmune diseases. ...

The overlapping geographical distribution of malaria and helminth infections has led to several studies in- vestigating the effect of co-infections by these parasites on the host. We investigated the impact of Necator ...

Context: Human immunodeficiency virus (HIV) is a well-known pathogen that causes acquired immunodeficiency syndrome (AIDS). The course of HIV infection and progression may be influ- enced by sickle cell traits. Objectives: ...

Many countries in Sub-Saharan Africa (SSA), did not achieve the Millennium Development Goal 4 target of reducing under-five mortality by two-thirds between 1990 and 2015. A large proportion of under-five deaths in SSA ...

Introduction: The impact of foodborne trematode infections is gaining recognition worldwide. Clonorchiasis and opisthorchiasis are some of the most neglected tropical foodborne diseases that pose a significant threat to ...